SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
The Neuroscientist
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Lin, D. A.
Right arrow Articles by Finklestein, S. P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Lin, D. A.
Right arrow Articles by Finklestein, S. P.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Reviews

{blacksquare} REVIEW : Basic Fibroblast Growth Factor: A Treatment for stroke?

David A. Lin

CNS Growth Factor Research Laboratory Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts

Seth P. Finklestein

CNS Growth Factor Research Laboratory Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts

Basic fibroblast growth factor (bFGF) is a polypeptide with potent trophic effects on brain cells. In particular, bFGF promotes the survival and outgrowth of brain neurons, and protects neurons against toxic processes that are important contributors to cell death after cerebral ischemia (stroke). Recent studies in animal models have suggested two potential uses of exogenously administered bFGF for the treatment of stroke: 1) intra venous bFGF to reduce infarct size in acute stroke, and 2) intracisternal bFGF to enhance neurological recovery in chronic stroke. Human clinical trials of the first of these applications are currently in progress. NEUROSCIENTIST 3:247-250,1997

Key Words: KEY WORDS Basic fibroblast growth factor • Cerebral Ischemia • Stroke

The Neuroscientist, Vol. 3, No. 4, 247-250 (1997)
DOI: 10.1177/107385849700300412
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 StrokeHome page
B. B. Johansson
Brain Plasticity and Stroke Rehabilitation : The Willis Lecture
Stroke, January 1, 2000; 31(1): 223 - 230.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. L. Boxer, H. Moreno, B. Rudy, and E. B. Ziff
FGF-2 Potentiates Ca2+-Dependent Inactivation of NMDA Receptor Currents in Hippocampal Neurons
J Neurophysiol, December 1, 1999; 82(6): 3367 - 3377.
[Abstract] [Full Text] [PDF]


Advertisement