The Neuroscientist

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lytton, W. W.
Right arrow Articles by Sober, S. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Lytton, W. W.
Right arrow Articles by Sober, S. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Neuroscientist, Vol. 5, No. 2, 100-111 (1999)
DOI: 10.1177/107385849900500214
© 1999 SAGE Publications

Reviews

{blacksquare} REVIEW : Computer Models of Stroke Recovery: Implications for Neurorehabilitation

William W. Lytton

Departments of Neurology, Neuroscience Program, University of Wisconsin Wm. S. Middleton VA Hospital

Jeanne M. Stark

Departments of Neurology and Anatomy

Dawayne S. Yamasaki

Departments of Anatomy Neuroscience Program,

Samuel J. Sober

University of Wisconsin Wm. S. Middleton VA Hospital

The persistence of cortical plasticity in the adult can help explain functional recovery after stroke. Computer modeling tools developed to explain the process of early development of sensory systems can be extended to help us relate cortical plasticity to both behavior and to underlying molecular and cellular mechanisms. Computer modeling results suggest a two-phase recovery process, involving immediate alterations in activity patterns caused by the loss of the infarcted neurons ("dynamic plasticity"), followed by true plastic changes as the new activity alters synaptic weights between neurons. Recognition of these two phases suggests that timing of physiotherapy and pharmacotherapy may play an important role in their efficacy. NEURO SCIENTIST 5:100-111, 1999

Key Words: KEY WORDS Computer simulation • Visual field • Plasticity • Cerebrovascular accident


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?