|
Sign In to gain access to subscriptions and/or personal tools.
|
Neuron: A Tool for Neuroscientists
M. L. Hines
Departments of Computer Science, Yale University, New Haven, Connecticut, michael.hines{at}yale.edu
N. T. Carnevale
Departments of Psychology, Yale University, New Haven, Connecticut
NEURON is a simulation environment for models of individual neurons and networks of neurons that are closely linked to experimental data. NEURON provides tools for conveniently constructing, exercising, and managing models, so that special expertise in numerical methods or programming is not required for its productive use. This article describes two tools that address the problem of how to achieve computational efficiency and accuracy.
Key Words: Computer model Computational neuroscience Neural model Spatial grid
The Neuroscientist, Vol. 7, No. 2,
123-135 (2001)
DOI: 10.1177/107385840100700207

CiteULike Complore Connotea Del.icio.us Digg Reddit Technorati Twitter What's this?
This article has been cited by other articles:

|
 |

|
 |
 
V. Volman, H. Levine, E. Ben-Jacob, and T. J. Sejnowski
Locally Balanced Dendritic Integration by Short-Term Synaptic Plasticity and Active Dendritic Conductances
J Neurophysiol,
December 1, 2009;
102(6):
3234 - 3250.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. N. Guzman, J. Sanchez-Padilla, C. S. Chan, and D. J. Surmeier
Robust Pacemaking in Substantia Nigra Dopaminergic Neurons
J. Neurosci.,
September 2, 2009;
29(35):
11011 - 11019.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Kanyshkova, M. Pawlowski, P. Meuth, C. Dube, R. A. Bender, A. L. Brewster, A. Baumann, T. Z. Baram, H.-C. Pape, and T. Budde
Postnatal Expression Pattern of HCN Channel Isoforms in Thalamic Neurons: Relationship to Maturation of Thalamocortical Oscillations
J. Neurosci.,
July 8, 2009;
29(27):
8847 - 8857.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. A. Deister, C. S. Chan, D. J. Surmeier, and C. J. Wilson
Calcium-Activated SK Channels Influence Voltage-Gated Ion Channels to Determine the Precision of Firing in Globus Pallidus Neurons
J. Neurosci.,
July 1, 2009;
29(26):
8452 - 8461.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Bogaard, J. Parent, M. Zochowski, and V. Booth
Interaction of Cellular and Network Mechanisms in Spatiotemporal Pattern Formation in Neuronal Networks
J. Neurosci.,
February 11, 2009;
29(6):
1677 - 1687.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Diwakar, J. Magistretti, M. Goldfarb, G. Naldi, and E. D'Angelo
Axonal Na+ Channels Ensure Fast Spike Activation and Back-Propagation in Cerebellar Granule Cells
J Neurophysiol,
February 1, 2009;
101(2):
519 - 532.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Day, D. Wokosin, J. L. Plotkin, X. Tian, and D. J. Surmeier
Differential Excitability and Modulation of Striatal Medium Spiny Neuron Dendrites
J. Neurosci.,
November 5, 2008;
28(45):
11603 - 11614.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. S. Gertler, C. S. Chan, and D. J. Surmeier
Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons
J. Neurosci.,
October 22, 2008;
28(43):
10814 - 10824.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. Z. Wetmore, E. A. Mukamel, and M. J. Schnitzer
Lock-and-Key Mechanisms of Cerebellar Memory Recall Based on Rebound Currents
J Neurophysiol,
October 1, 2008;
100(4):
2328 - 2347.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Johnston, S. J. Griffin, C. Baker, A. Skrzypiec, T. Chernova, and I. D. Forsythe
Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons
J. Physiol.,
July 15, 2008;
586(14):
3493 - 3509.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Sylantyev, L. P. Savtchenko, Y.-P. Niu, A. I. Ivanov, T. P. Jensen, D. M. Kullmann, M.-Y. Xiao, and D. A. Rusakov
Electric Fields Due to Synaptic Currents Sharpen Excitatory Transmission
Science,
March 28, 2008;
319(5871):
1845 - 1849.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
F. Maingret, B. Coste, F. Padilla, N. Clerc, M. Crest, S. M. Korogod, and P. Delmas
Inflammatory Mediators Increase Nav1.9 Current and Excitability in Nociceptors through a Coincident Detection Mechanism
J. Gen. Physiol.,
February 25, 2008;
131(3):
211 - 225.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. J. Calin-Jageman, M. J. Tunstall, B. D. Mensh, P. S. Katz, and W. N. Frost
Parameter Space Analysis Suggests Multi-Site Plasticity Contributes to Motor Pattern Initiation in Tritonia
J Neurophysiol,
October 1, 2007;
98(4):
2382 - 2398.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Sakurai, R. J. Calin-Jageman, and P. S. Katz
Potentiation Phase of Spike Timing-Dependent Neuromodulation by a Serotonergic Interneuron Involves an Increase in the Fraction of Transmitter Release
J Neurophysiol,
October 1, 2007;
98(4):
1975 - 1987.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. M. Kahlig, S. N. Misra, and A. L. George Jr
Impaired Inactivation Gate Stabilization Predicts Increased Persistent Current for an Epilepsy-Associated SCN1A Mutation
J. Neurosci.,
October 25, 2006;
26(43):
10958 - 10966.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. G. Meuth, T. Kanyshkova, P. Meuth, P. Landgraf, T. Munsch, A. Ludwig, F. Hofmann, H.-C. Pape, and T. Budde
Membrane Resting Potential of Thalamocortical Relay Neurons Is Shaped by the Interaction Among TASK3 and HCN2 Channels
J Neurophysiol,
September 1, 2006;
96(3):
1517 - 1529.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
O. Zaika, L. S. Lara, N. Gamper, D. W. Hilgemann, D. B. Jaffe, and M. S. Shapiro
Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels
J. Physiol.,
August 15, 2006;
575(1):
49 - 67.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. B. Rubin and T. A. Cleland
Dynamical Mechanisms of Odor Processing in Olfactory Bulb Mitral Cells
J Neurophysiol,
August 1, 2006;
96(2):
555 - 568.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. Gold, D. A. Henze, C. Koch, and G. Buzsaki
On the Origin of the Extracellular Action Potential Waveform: A Modeling Study
J Neurophysiol,
May 1, 2006;
95(5):
3113 - 3128.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Nieus, E. Sola, J. Mapelli, E. Saftenku, P. Rossi, and E. D'Angelo
LTP Regulates Burst Initiation and Frequency at Mossy Fiber-Granule Cell Synapses of Rat Cerebellum: Experimental Observations and Theoretical Predictions
J Neurophysiol,
February 1, 2006;
95(2):
686 - 699.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
N. N. Urban and J. B. Castro
Tuft Calcium Spikes in Accessory Olfactory Bulb Mitral Cells
J. Neurosci.,
May 18, 2005;
25(20):
5024 - 5028.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. M. Leao, C. Kushmerick, R. Pinaud, R. Renden, G.-L. Li, H. Taschenberger, G. Spirou, S. R. Levinson, and H. von Gersdorff
Presynaptic Na+ Channels: Locus, Development, and Recovery from Inactivation at a High-Fidelity Synapse
J. Neurosci.,
April 6, 2005;
25(14):
3724 - 3738.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Murbartian, J. M. Arias, and E. Perez-Reyes
Functional Impact of Alternative Splicing of Human T-Type Cav3.3 Calcium Channels
J Neurophysiol,
December 1, 2004;
92(6):
3399 - 3407.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. A. Prescott and Y. De Koninck
Gain control of firing rate by shunting inhibition: Roles of synaptic noise and dendritic saturation
PNAS,
February 18, 2003;
100(4):
2076 - 2081.
[Abstract]
[Full Text]
[PDF]
|
 |
|
|