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First published on October 2, 2007, doi:10.1177/1073858407304393

The Neuroscientist 2007;13:657.

A more recent version of this article appeared on December 1, 2007


Article

Neuron–Glial Communication at Synapses: Insights From Vertebrates and Invertebrates

Keith K. Murai* and Donald J. van Meyel

Centre for Research in Neuroscience, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada

* To whom correspondence should be addressed. E-mail: keith.murai{at}mcgill.ca.


   Abstract
Glial cells are instrumental for many aspects of nervous-system function. Interestingly, complex neuron–glial interactions at synapses are commonly found in both invertebrates and vertebrates. Although these interactions are known to be important for synaptic physiology, the cellular processes and molecular mechanisms involved have not been fully uncovered. Identifying the common and unique features of neuron–glial interactions between invertebrates and vertebrates may provide valuable insights into the relationship of neuron–glial cross-talk to nervous-system function. This review highlights selected studies that have revealed structural and functional insights into neuron–glial interactions at synapses in invertebrate and vertebrate model systems. DOI: 10.1177/1073858407304393
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?